Giant
Intracranial Aneurysm in a Ten-Year-Old
Boy with Parry Romberg Sindrome.
A Case Report and Literature
Review
T.
Bosman,
J.
van
Beijnum,
M.A.A.
van
Walderveen,
P.A.
Brouwer
Summary -
Parry-Romberg
syndrome
(PRS)
is
a
rare
acquired
syndrome
consisting
of
progressive
hemiatrophy
of
the
face.
We
present
a
child
with
PRS
and
progressive
neurological
deficit
caused
by
a
giant
intracranial
aneurysm
and
reviewed
the
literature
concerning
all
intracranial
abnormalities
in
patients
with
PRS.
A
literature
search
identified
27
articles
reporting
on
88
patients
with
PRS
and
intracranial
abnormalities.
Ipsilateral
brain
calcification
and
hemiatrophy
are
the
most
prominent
features
on
CT
scan
and
hyperintense
white
matter
lesions
are
most
frequently
seen
on
T2-weighted
MRI.
Although
lacking
precise
prevalence
data,
intracranial
abnormalities
are
not
uncommon
in
patients
with
PRS. We
found
three
other
PRS
patients
with
intracranial
aneurysms.
Our
case
and
literature
search
suggests
a
possible
association
between
PRS
and
intracranial
aneurysms.
We
consider
this
association
important
for
clinical
practice
and
recommend
including
intracranial
vascular
diseases
in
the
differential
diagnosis
when
dealing
with
a
PRS
patient
with
neurological
symptoms.