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VOLUME 16 - 4
December 2010

Instructions for Authors
First formulated in November, 1995 • Revised on January 26, 2010

Interventional Neuroradiology (INR) is a clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiological techniques and to the treatment of neurovascular and spinal disorders managed by such approaches. The Journal’s scope includes research in neurovascular diseases and in the endovascular treatment of neurological and spinal disorders including their percutaneous management. Submissions suitable for the Journal include observational studies, clinical trials, epidemiological work, reports on health services and outcomes, and advances in applied (translational) and/or basic research.
The instructions for submission of articles to INR follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals of the International Committee of Medical Journal editors (ICMJE, http://www.icmje.org), if not otherwise indicated below.

Research and publication ethics
For the policies on research and publication ethics not stated in these instructions, the Guidelines on Good Publication Practice issued by the Committee on Publication Ethics should be applied.

  • Author responsibility for originality: Each author acknowledges responsibility for the integrity of the manuscript, assures the originality of the paper, and guarantees that submitted manuscripts do not contain previously published material and are not under consideration for publication elsewhere. If the submitted manuscript builds on or includes parts of previously published articles, authors are encouraged to enclose copies of the articles with the new submission. The Editors reserve the right to request the original data obtained in the investigation.
  • Registration of clinical trial research: Any research that includes clinical trials should be registered with the primary national clinical trial registration authority accredited by WHO (http://www.who.int/ictrp/network/primary/en/index.html) or ICMJE.
  • Disclosure statement: This is not intended to prevent authors with potential conflicts of interest from contributing to INR. Rather, the Journal will place on record any relationship that may exist with disclosed, or competing, products or firms. Disclosed information will be held in confidence during the review process and the Editors will examine any printed disclosure accompanying a published article. Authors are responsible for notifying the Journal of financial arrangements including, but not limited to, agreements for research support including provision of equipment or materials, membership of speaker bureaus, consulting fees, or ownership interests. It is important that disclosure statements be updated promptly to reflect any new relationships that arise after initial submission of the manuscript. If the study is supported by a commercial sponsor, the authors must document the input of the sponsoring agency in study design, data collection, analysis of results, interpretation of data, and report writing. It is important to specify whether the sponsors could have suppressed or influenced publication if the results were negative or detrimental to the product they produce. Authors should also state if the company was involved in the original study design, the collection and monitoring of data, analysis and/or interpretation, and/or the writing and approval of the report. (Download form: Conflict of Interest/Disclosures).
  • Statement of human and animal rights: Manuscripts involving examination of volunteers and patients must include a statement that the study protocol has been approved by an institutional review board (IRB) and that the subjects gave informed consent, thus meeting the standards of the Declaration of Helsinki (revised version) developed by the World Medical Association as a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and data (http://www.wma.net). With animal subjects, research should be performed based on a National or Institutional Guide for the Care and Use of Laboratory Animals, and ethical treatment of all experimental animals is expected throughout all experiments.
  • Duplicate/Redundant publication: INR only accepts manuscripts describing original research. The editorial office of the INR does not accept duplicate submission or redundant publication. Redundant (or duplicate) publication is publication of a paper that overlaps substantially with a paper already published in print or electronic media as defined by the updated ICMJE guidelines that cover allegations of scientific misconduct. When submitting a paper, authors should make a full statement to the Editor on all submissions and previous reports that might be regarded as redundant publication of the same or similar work. If authors believe that their manuscript may be considered redundant, they should address this issue in a letter to the Editor accompanying the submission. The authors should also explain in the letter how their report overlaps already published material, or how it differs. Copies of such published material should be included with the submitted paper to help the Editor examine the possibility of redundant publication. If redundant publication is attempted without such notification, authors should expect editorial action to be taken. At the very least, rejection of the manuscript may be expected.
  • Authorship: The Editors consider authorship to belong to those persons who accept intellectual and public responsibility for the statements made and results reported. By submitting a manuscript for publication, each author acknowledges having made a substantial contribution to the concept and design of the study, the analysis and interpretation of the results, and the writing of the paper, in addition to having approved the final submitted version. Authorship should not be attributed to Departmental Chairs not directly involved in the study, to physicians or technicians who provided routine services, or to technical advisors. A group study should carry the group name and reference contributing authors in the Acknowledgments.

Peer review process
Papers are accepted on the understanding that they are subject to peer review, editorial revision, and, in some cases, comment by the Editors. Manuscripts are examined by independent peer reviewers. Articles and other material published in the Journal represent the opinions of the authors and should not be construed to reflect the opinions of the publisher.

Language
The official language of INRis English. Most papers in INR have been written by non-native English speakers, and they will also be read by many non-native speakers. For the purposes of clarity, it is strongly recommended that authors not fluent in English have their manuscript professionally edited for English usage prior to submission. A professional editor will improve the English to ensure that author meaning is clear and to identify problems that require author review. Authors are invited to contact the INR language editor Anne Collins (collins@iol.it) for referral to professional English language editing services. Authors should make contact with and arrange payment to their chosen editing service directly. Please note that the use of such a service is at the author's own expense and risk and does not guarantee that the article will be accepted for publication. Centauro Publishers does not receive any commission or other benefit from editing services. Accordingly, Centauro Publishers neither endorses nor accepts any responsibility or liability for such editing services.

Copyright and purchase of Offprints  
All articles published in INR are protected by copyright, which embraces the exclusive right to reproduce and distribute the article (e.g., as offprints), as well as all translation rights. No material published in the Journal may be reproduced without written permission from the publisher. INR offers authors a complimentary hard copy and .pdf file of the issue in which their article is published, for personal use. To purchase offprints of articles published by INR please contact Centauro Srl for a quotation at serena.preti@centauro.it.

Publication Types
Original Research Articles are full-length research papers, which are favored by INR. Articles cover topics relevant to clinical studies, and may include both basic and experimental work (maximum length: 5,000 words)
Review Articles are comprehensive, state-of-the-art papers focusing on important clinical problems and should address a specific topic in a scholarly manner. Such articles may be invited by the Editor or may be unsolicited reviews (maximum length: 5,000 words).
Case Reports/Technical Notes should be unusually educational and medically important. Although INR preferentially encourages submission of full-length Original Research Articles, the Journal will consider publication of a limited number of concise Case Reports and Technical Notes. Such papers are limited to 75 words of Summary, 1,500 words of text including references and tables, and an average single-column of images. There should be no more than five authors.
Editorials are usually invited by the Editor.
Editorial Comments are specific comments on the articles published in INR and are usually invited by the Editor (maximum length: 500 words)
Letters to the Editor contain constructive criticism of a specific paper published by INR. Letters dealing with subjects of general interest within the field of INR, or personal opinions on a specific subject within the ambit of INR, may also be accepted (maximum length including references: 1,000 words).

Electronic submission of manuscripts
INR provides an electronic submission system (Editorial Manager) and review process to promote expeditious peer review. Manuscripts should be submitted electronically to the following URL: http://www.editorialmanager.com/in/. Questions about manuscripts under consideration may be addressed to the editorial office:

Interventional Neuroradiology
Centauro S.R.L.
Via del Pratello, 8
I-40122 Bologna – Italy
Tel: +39.051.227634
Fax: +39.051.220099
E-mail: adriana.dallocca@centauro.it

All authors listed on the manuscript must complete forms, found within Editorial Manager, entitled Conflicts of Interest/Disclosures, Copyright Transfer Agreement, Financial Support, Exclusive Publication Statement, and Author Contribution Form. Submissions not containing completed forms from every author will not progress to peer review. Prior to submitting any paper, please follow the instructions given below. Please note that an author must have an e-mail address to use the online submission system.

MANUSCRIPT PREPARATION
Original research should be organized in the customary format, as described below. The text of the manuscript should be submitted as a single document with the following sections (in order):

  • Author Information Page (First page)
    Full title of the article, authors' names, highest academic degree earned by each author, authors' affiliations, name and complete address for correspondence, address for reprints if different from address for correspondence, fax number, telephone number, and e-mail address.
  • Acknowledgments and Funding Page (Second page)
    The Acknowledgments section lists all funding sources for the research of the study, and details substantive contributions of individuals. The authors must reveal all possible Conflicts of Interest/Disclosures.
  • Title Page (Third page)
    The full title, itemized list of the number of tables, the number and types (color or black-and-white) of figures, and three-to-five key words for use as indexing terms should be included. Appropriate key words should be selected from the Medical Subject Heading. The word count of the text should be specified.
  • Summary
    A summary of up to 250 words should summarize the problems presented and describe the studies undertaken, results and conclusions. Since the abstract must be explicative, the abbreviations must be reduced to a minimum and explained. References should not be cited in the abstract.
  • Text
    Typical main headings include Introduction, Materials and Methods, Results, Discussion, and Conclusions. Abbreviations must be defined at first mention in the text, tables and figures. The complete names and addresses of manufacturers of any equipment used in Materials and Methods must be supplied. If animals are used in experiments, state the species, the strain, the number of animals used, and any other pertinent descriptive characteristics. If human subjects or patients are employed, provide a table with relevant characteristics. When describing surgical or neurointerventional procedures on animals, identify the pre-anesthetic and anesthetic agents used, and state the amount or concentration and the route and frequency of administration of each agent. Generic names of drugs must be given. Manuscripts that describe studies on humans must indicate that the study was approved by an Institutional Review Committee and that all subjects gave informed consent. Reports of studies on both animals and humans must indicate that all procedures followed were in accordance with institutional guidelines.
  • References
    Citations should be listed in order of appearance in the text, and between square brackets [ ]. References must be listed at the end of the text in the order of citation. Journal titles should be abbreviated according to Index Medicus. For citation rules not specified here, authors should refer to the NLM Style Guide for Authors, Editors, and Publishers (http://www.nlm.nih.gov/citingmedicine). All references must be checked by the author(s).
  • Journal article: Laredo JD, Bard M. Thoracic spine: percutaneous trephine biopsy. Radiology. 1986;160: 485-9.
    Journal article if the number of authors is more than six: list the first three authors followed by et al.
    Geibprasert S, Krings T, Pereira V, et al. Clinical characteristics of dural arteriovenous shunts in 446 patients of three different ethnicities. Intervent Neuroradiol. 2009; 15: 395-400.
    Entire book: Valavanis A. Medical radiology: interventional neuroradiology. Heidelberg: Springer Verlag; 1993.
    Part of book if number of authors is more than two: Bonneville JF, Clarisse J, et al. Radiologie interventionnelle. In: Manelfe C ed. Imagerie du rachis et de la moelle. Paris: Vigot Editeur; 1989. p. 761-776.

  • Tables
    Each table must be typed on a separate sheet and double-spaced, if possible. Tables should be numbered using the Arabic system, followed by a brief informative title. Use type of the same font and size as employed in the text. Include footnotes at the bottom of each table. Tables must be numbered in the order cited in the text. Tables should not duplicate data given in the text or figures.
  • Figure Legends
    Provide figure legends on a separate sheet. Legends must be double-spaced, and figures must be numbered in the order cited in the text.

  • Figures
    Figures should preferably be submitted online to http://www.editorialmanager.com/in/. The time required to send files will vary depending on the number of figures, but image resolution must not be reduced to decrease transmission time. When labeling the figures, please ensure that the label corresponds to the figure number.
    Digital images (originals or images acquired by a scanner) must meet the following criteria:
    Black-and-white figures: Images must be acquired using the grey scale with a minimum resolution of 300 pixels per inch or 150 pixels per cm. Images must have a base of at least 8.1 cm for one item or a minimum base of 16.9 cm for several items.
    Color figures: Images must be acquired using the full color CMYK method with a minimum resolution of 300 pixels per inch or 150 pixels per cm. Images must have a base of at least 8.1 cm for one item or a minimum base of 16.9 cm for several items. The RGB method is recommended for video reproductions only, as the quality of printed figures is poor.
    Images must be saved in .tiff format. Images in .jpg format are not acceptable as details tend to be lost upon scanning, even at high resolution. Image definition also depends on the enlargement factor. Thus, a large low-resolution image can be proportionally reduced (by 24%) for publication, thereby permitting optimal presentation in print. However, enlargement of a small high-resolution image will highlight all flaws, yielding a pixelated effect.
    Do not submit figures already paged in Word, PowerPoint, or other documents, or images inserted in web pages. Such images are of low-resolution and are unsuitable for printing.
    Figures in .dcm (Dicom) format may be submitted as .dcm or .tiff files. The editorial office will process such images for printing.
    Illustrations may be compressed using the StuffIt, Aladdin or Zip programs.
    Do not label an image with arrows, numbers or letters, but rather indicate on a duplicate copy or a sketch where such indications are desired.
    Authors are advised to refer to the Journal guidelines when formatting their work. Otherwise the editorial office may return a submission to the authors for improvement before any Editor is assigned.
    If it is not possible to send figures via the Internet, images may be sent by express courier in one of the following formats:
    Original x-ray films, slides, or glossy or opaque prints. Clearly indicate on the back of the image the first author’s name and the number corresponding to the figure caption and citation in the text.
    Figures may be submitted on a CD-ROM or DVD, copied in ISO9006 format legible on both PC and MAC. Floppy disks are not recommended. Clearly indicate on one side of the figure both the top of the figure and the figure number. Do not label the actual image with arrows, numbers, or letters, but rather indicate the top and figure number on a duplicate copy or on a sketch. Do not cut or attach figures with adhesive tape or use paper clips. If images are sent offline, thumbnails of the images should be uploaded as a submission item online, together with the manuscript, to allow the publishers to reserve space for the original high-resolution images. Authors are reminded that manuscripts must be sent online via Editorial Manager even when authors choose off-line figure submission. All off-line material should be sent to the editorial office.


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