Oxygen-Ozone Treatment of Carpal Tunnel Syndrome. Retrospective Study and Literature Review of Conservative and Surgical Techniques
A. Zambello, L. Fumagalli, B. Fara, M.M. Bianchi
SUMMARY - Carpal tunnel syndrome (CTS) is a neuropathy caused by median nerve entrapment under the transverse carpal ligament at the wrist. It is a common condition presenting with pain (especially at night), paraesthesia and in advanced disease muscular hypertrophy and functional deficit. Diagnosis is based on clinical findings and mainly electromyography. The use of wrist-hand appliances is decisive in patients with acute CTS to reduce pressure within the carpal tunnel. Oral NSAIDs and methylprednisolone have proved effective short-term treatments. Local steroid injection is indicated in patients without major electromyographic abnormalities, persistent paraesthesia, impaired sensitivity, weakness or hypertrophy of the thenar eminence. Infiltration of oxygen-ozone gas mixture in the same patients has yielded short, medium and long-term outcomes similar to those following steroid injection. A small group of patients maintained the therapeutic benefit two years after treatment. Unsatisfactory response to local oxygen-ozone treatment is an indication for surgery.
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