Ozone Therapy: A Clinical Study on Pain Management
L. Re, G. Martínez-Sánchez, G. Malcangi, A. Mercanti, V. Labate
SUMMARY - Ozone therapy has been widely used in many countries for many years and has recently continued to spread in the wake of an increasing number of basic and clinical papers published in international journals. Many of the basic mechanisms of ozone action are now well outlined. In addition, the modulation of interleukin productions and of some biochemical pathways related to inflammation and pain indicate the rationale of ozone use in many pathological conditions related to pain. This paper reports on data collected in patients treated in the last three years for pain-related disorders due to sport injury (232 subjects) or inflammatory disorders (770 subjects). The evolution of patients was followed using the Overall Patient Satisfaction Scale. The maximal score (8-10) corresponding qualitatively to “very good” was reached in 80% of patients. A rapid and sustained success was reached in pubalgy to a score 8-10 as soon as therapy was started. A progressive evolution in time was reached to a score 8-10 in patients with pain from inflammatory disorders. However, the maximal score in inflammatory joint diseases was 6-8 (qualitatively “good”). No side-effects were recorded at short and long-term follow-up. In our experience, O2-O3 treatment of pain and inflammatory diseases has revolutionized the management of pain caused by radiculopathy and joint disease.
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